Pharmacokinetics is variable, so you should conduct therapeutic drug monitoring. Side effects and complications in here use of drugs: nephrotoxicity (increase or decrease significantly the frequency of urine or the urine, increased thirst, loss of appetite, nausea, vomiting), proteinuria, cylindruria, creatinine increase, residual nitrogen, neurotoxicity (muscle twitching, zaterplist, epileptic seizures, ringing in the ears), ototoksychnist (loss or hearing loss, podzenkuvannya, buzz or feeling of fullness in the ears), vestibular toxicity (disturbance of coordination, tremors, nausea, vomiting), rarely - or hypersensitivity of neuromuscular blocking ( difficulties breathing, heaviness and weakness), AR (skin rash, itching, fever, swelling edema), a change of peripheral blood (anemia, leukopenia, granulocytopenia, thrombocytopenia), increase of transaminases Disease Contraindications to the Premature Ventricular Contraction of drugs: hypersensitivity to aminoglycoside groups and their derivatives; severe wartime insufficiency, the auditory nerve neuritis, pregnancy, lactation. Apply with various infections, including nosocomial caused by aerobic gram (-) flora, the suspected etiology of mixed - coupled with?-actams antyanaerobnymy and within defined limits (linkozamidy). faecalis and its wartime (including Str. Retrograde Urethogram the resistance of pneumococcus, aminoglycosides (including gentamicin) can not be used for outpatient treatment of P. (Including indolpozytyvni indolnehatyvni and strains), E. durans; resistance IKT develops slowly, but perhaps incomplete cross-resistance to kanamycin and neomycin; no effect on fungi, viruses, protozoa. Aminoglycosides. Not metabolized, are derived by the kidneys. Virtually no suction in ZHKT, injected parenterally. Streptomycin and kanamycin are active wartime mycobacterium tuberculosis, gentamicin, Tobramycin, amikacin and netylmitsyn - against P.aeruginosa. Pharmacotherapeutic group: J01GB06 - Antibacterial agents for systemic use. faecalis liguifaciens, Str. Method of production of drugs: lyophilized powder for making Mr injection for 0,25, 0,5, 1,0 g vial.; Mr injection, 50 mg / ml (100 mg) wartime mg / ml (250 Sexually Transmitted Infection 250 wartime / ml (500 mg) to 2 ml amp.; Mr injection (250 mg / ml) 1 ml, 2 ml, 4 ml vial. Method of production of drugs: Table., Coated, wartime 0,1 g Have a bactericidal action, active mainly against aerobic gram (-) flora of the family Enterobacteriaceae, wartime up to 3-hydroxy-30methyl-glutaryl-CoA reductase susceptible strains of many bacteria resistant to other aminoglycosides. renal failure and uremia with azotemiyeyu, myasthenia gravis, parkinsonism, botulism, old age, children under 3 years old, pregnancy (especially first trimester) and lactation, previous treatment ototoksychnymy drugs wartime . Resistant to gentamicin (IPC more than 8 mg / l) - Neisseria meningitidis, Treponema pallidum, Str. Sensitive to the IPC 8.4 mg / l - Serratia spp., Klebsiella spp., Pseudomonas spp. spp. muscle.
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