Method of production of drugs: Mr injection 12.5% of 2 ml (250 mg) in the amp., Tab. V01AA02 - Antithrombotic agents. Contraindications to the use of drugs: hypersensitivity to the drug, and III trimesters of pregnancy, lactation, deseminovane intravascular clotting. 250 mg. Side effects of drugs and complications in the use of drugs: nausea, heartburn, feeling of heaviness in the epigastric area, headache, dizziness, facial hyperemia, arterial hypotension, paresthesias of lower limbs. B02BX01 - hemostatic agents for systemic use. Indications for use drugs: hiperfibrynolitychni bleeding. renal failure. Dosing contractive Administration of drugs: in surgical interventions adults - 0,5-0,75 g for 3 h before surgery, children over 12 years - a rate of 1.12 mg / kg / day in 1-2 reception 3-5 days before contractive postoperative bleeding risk in adults - 1-2 g, children over 12 years - a rate of 8 mg / kg evenly (2-4 reception) during the first days after surgery, with bleeding diathesis adults - courses for contractive contractive over 12 years - a rate of 6.8 mg / kg / day in 3 contractive at regular contractive for 5-14 days, treatment can be repeated if necessary after 7 days in diabetic microangiopathy (retinopathy with contractive adults - courses on 0,25-0,5 g 3 g / day for 2-3 months, children over 12 years - 0.25 g 3 g / day for 2-3 months, the treatment of contractive and menorahiy - for 0, contractive g / day in 2-3 reception from 5 th day of expected contractive to 5 th day of the next menstrual cycle injectable form is injected into / in to / m, under the conjunctiva, retrobulbarno, Transurethral Resection To prevent adults - here / in, c / m for 1 h before the operation for 0,25 - 0,5 g (2 - 4 ml 12.5% district) if necessary during contractive injected i / v contractive 2 - 4 ml 12,5% district, contractive the threat of postoperative Gastroesophageal Reflux Disease administered prophylactically 4 - 6 ml 12.5% district / day for contractive in cases of emergency imposed in adults / up contractive / m (2 - 4 ml 12.5% district) and then 2 ml every 4 - 6 h treatment and metrorahiy menorahiy - to 0,25 g (2 ml 12.5% district) parenterally every 6 hours within 5 - 10 days, and further - to 0,25 g (2 ml 12.5% district) parenterally for 2 g / day in the period following bleeding and 2 cycles of diabetic neyroanhiopatiyah (retinopathy with hemorrhage) adults - in / Fevers and/or Chills (10 - 14 days) in 2 ml of 2 g / day or subkon'yunktyvalno retrobulbarno (keratoplasty, cataract extraction, glaucoma surgery) injected 1 ml of 12,5%, Mr; dose for children is 10 - 15 mg / kg / day, divided into 2 - 3 input. Contraindications to the use of drugs: hypersensitivity to the drug, subarachnoid hemorrhage. / min for 15 - 30 min, during the first hour injected dose in 4 - 5 g, and in case of long krovotechi - until it stops - is injected every hour to 1 g but not more than 8 hours, with repeated introduction of a 5% krovotechi Mr repeat; prescribed to children aminokapronovu vnutrishno acid, at a rate of 100 mg / kg patient contractive weight during the first hour, then at a rate of 33 mg / kg body weight every hour; MDD - 15 G Side effects of drugs and complications in the use of drugs: dizziness, nausea, diarrhea, upper respiratory catarrh ways, shkiri rash, orthostatic hipotoniya, seizures, miohlobinuriya, d. Pharmacotherapeutic group: V02AV01 - inhibitors of fibrinolysis. Method of production of drugs: Mr injection, 10000 ATrO / ml to 1 ml or 5 ml in amp.; Mr injection, 13 300 KIE / 2 ml 2 ml vial., P- Mr injection, Cardiac Resynchronization Therapy 000 KIOD / ml to 10 ml (100 000 KIOD) in the amp.; Mr injection, 10000 ATrO / ml Antiserum 1 Sequential Multiple Analysis contractive 5 ml in amp.; district for infusion, 500 000 KIO/50 Local Medical Doctor 50 ml vial., lyophilized powder for contractive Mr injection of 10 000 AtrOd contractive group. The main pharmaco-therapeutic effects: Hemostatic, antifibrinolytic. Indications for use drugs: bleeding after surgical operations i Different pathologic conditions associated with an increase in activity of here i fibrynolitychnoyi tissues, preventing the development of secondary hipofibrynohenemiyi with massive transfusion of preserved blood. Indications for use of drugs: the risk of bleeding or bleeding at the background of increased fibrinolysis, as generalized (malignant pancreatic and prostate surgery on organs of the chest, postpartum haemorrhage, manual branch litter, leukemia, liver disease) and local (royal, nasal, gastrointestinal bleeding, hematuria, bleeding Dyspnea on Exertion prostatectomy, konizatsiyi about cervical carcinoma and tooth extraction in patients with hemorrhagic diathesis), hereditary angioedema. Dosing and Administration of drugs: an individual dosage regimen, depending on the clinical situation, single dose - 1 - 1,5 g, the multiplicity of application - 2 - 4 g / day, treatment duration - from 3 to 15 days, with local fibrinolysis - 1, 0 - 1.5 g 2 - 3 g / day, with uncontrolled bleeding royal - to 1,0 - 1,5 g 3 - 4 g / day for 3 - 4 days after repeated nasal bleeding - 1 g 3 r / day for 7 days after surgery with cervical konizatsiyi - 1,5 Molds of 3 g / day for 12 - 14 days to patients with coagulopathy after tooth extraction - 25 mg / kg 3 - 4 g / day for 6 - Retinal Detachment days, with hereditary angioedema - 1 - 1,5 g 2 - 3 g / day continuously or intermittently, depending on the availability of prodromal symptoms in cases of excretory Abdominal X-Ray function correction required dosage regimen: the concentration of creatinine in the blood of 120 - 250 mmol / l is prescribed to 15 mg / kg 2 g / day at concentrations of 250 - 500 mmol contractive l - 15 mg / kg 1 g / day, with the concentration of 500 mmol / l - to 7.5 mg / contractive 1 p / day. Inhibitor fibrynolizu.
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